Brazil Sees Highest-Ever Bioinput Approvals in 2025 Alongside 912 Pesticide Registrations and Illegal Seizures

Brazil’s 2025 Pesticide Registration: Record Bioinputs, 912 Registrations and Rising Illegal Seizures

12 January 2026, São Paulo: Brazil closed 2025 with a record number of pesticide and bioinput registrations, while simultaneously intensifying enforcement against illegal pesticides, according to the Ministry of Agriculture and Livestock (Mapa). Official data published under Act No. 63 by the General Coordination of Pesticides and Related Products (CGAA/SDA/Mapa) show continued regulatory expansion alongside stricter market surveillance.

Registration outcomes and portfolio expansion

During 2025, Brazil approved one previously unpublished chemical active ingredient, 101 equivalent or generic products, and 15 bioinputs. By year-end, total registrations reached 912 products, including 323 technical-grade products intended exclusively for industrial formulation and not for direct sale to farmers.

Bioinputs emerged as a defining feature of the year. 162 bioinput products were approved—the highest annual figure recorded in Brazil—covering biological, microbiological and biochemical formulations, plant extracts, growth regulators and semiochemicals, including products suitable for organic agriculture. The regulatory authorities also approved six new technical products and 19 formulated products containing new active ingredients, reinforcing the gradual modernization of Brazil’s crop protection portfolio.

New active ingredients and resistance management

The introduction of new active ingredients remains strategically significant for Brazil’s phytosanitary framework. Unlike equivalent products, new molecules broaden available modes of action, support integrated pest and disease management strategies, and help mitigate resistance risks.

In 2025, Brazil registered the active ingredients Ipflufenoquine, Fluoxastrobin, Fluazaindolizine, Isopirazam, Fenpropidin and Ciclobutrifluram. Their approval reflects continued investment in innovation and aligns Brazil’s regulatory landscape more closely with global crop protection trends.

Dominance of equivalent products and process reforms

Equivalent and generic products accounted for the majority of registrations, consistent with policies aimed at increasing competition, stabilizing supply and reducing input costs. Mapa noted that a portion of the approvals resulted from judicial decisions linked to missed statutory deadlines, including applications originally submitted in 2015 and 2016.

To streamline regulatory workflows, Mapa issued Act No. 62 in December 2025, introducing standardized procedures for registration and post-registration applications. Since September 15, 2025, all new submissions have been routed exclusively through the Electronic Information System (SEI/Mapa). Applications submitted prior to this date continue under their original procedures, preserving legal certainty.

Registration volumes do not equal field usage

Authorities reiterated that registration numbers should not be interpreted as a proxy for pesticide use. Actual market demand is shaped by agronomic, climatic and economic factors. National data indicate that in 2024, 58.6% of registered chemical pesticide trademarks and 13.6% of active ingredients were not commercialized.

Regulation and illegal pesticide enforcement

Brazil’s pesticide approval system operates through a tripartite model involving technical assessments by National Health Surveillance Agency, Ibama, and the Ministry of Agriculture and Livestock. Registrations are granted only after all three authorities issue favorable technical opinions.

Alongside regulatory approvals, enforcement actions were expanded in 2025. Mapa issued technical review notices for several active ingredients and, under Act No. 61 of December 22, 2025, ordered the precautionary suspension of 34 pesticide registrations. Inspection operations led to the seizure of 1,946 litres of illegal pesticides, underscoring ongoing challenges related to illicit products in the supply chain.

Outlook for 2026

The 2025 measures form part of Brazil’s broader regulatory reform agenda under Law No. 14,785/2023, which introduced a unified protocol model, enhanced traceability and technical prioritization. Mapa, working with Anvisa and Ibama, is advancing the Unified System of Information, Petition and Electronic Evaluation (SISPA), scheduled for implementation in 2026.

Officials say the dual focus on innovation and enforcement is intended to strengthen regulatory credibility, support sustainable intensification and align Brazil’s crop protection framework with evolving global standards.

Also Read: Brazil Approves 912 Pesticide Registrations in 2025

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