TAHITI platform

Get the latest TAHITI platform news, research and developments covering Spearhead Bio’s plant genome-engineering technology designed to enable precise insertion, replacement, copying, rearrangement and stacking of large DNA sequences in crop genomes. The platform combines CRISPR-based targeting with transposable-element machinery to address one of the limitations of conventional genome editing: the controlled insertion of larger genetic sequences.

TAHITI stands for Transposase Assisted Homology Independent Targeted Insertion. The technology uses CRISPR-Cas9 or Cas12a to identify a specific genomic location, while an attached transposase helps move DNA cargo into the targeted site. The approach is being developed for both GMO and non-GMO crop applications, including gene replacement, trait stacking and introduction of larger genetic sequences. Spearhead Bio has reported work in crops including soybean, corn, cassava and the model plant Arabidopsis.

Find news on TAHITI platform development, crop genome engineering, CRISPR technology, gene insertion, gene replacement, trait development, research partnerships, licensing and agricultural biotechnology investment. Recent developments include Spearhead Bio’s $1.62 million seed funding round in September 2026 to advance the technology and expand its crop applications, alongside partnerships with industry and research organisations. Coverage also tracks developments in large-DNA genome editing and emerging technologies designed to accelerate the development of improved crop traits.